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Primary peritoneal cancer is a rare type of cancer that develops in the peritoneum, which is the lining of the abdomen. It shares similarities with ovarian cancer and is often treated in the same way. However, primary peritoneal cancer arises from cells in the peritoneal cavity, while ovarian cancer originates from the ovaries.

The exact cause of primary peritoneal cancer is unknown, but it is believed to be related to genetic mutations and family history.