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Sezary syndrome, also known as Sezary syndrome mycosis fungoides, is a rare type of lymphoma, which is a cancer of the lymphatic system. It is a variant of cutaneous T-cell lymphoma (CTCL) and is characterized by a specific set of symptoms.

Sezary syndrome typically affects older adults and is more common in men than women. The exact cause of this cancer is unknown, but it is believed to be linked to mutations in the DNA of T-lymphocytes, which are a type of white blood cells that play a crucial role in the immune system.